I don't know based on the rulebook. The rulebook does not explicitly address whether a single ability can allow multiple benefits or exchanges in one activation, nor does it provide specific instructions for resolving such exchanges.

Relevant Information:

• Page 5 mentions that benefits from cave cards and player mat spaces are optional and typically advantageous. It also specifies that certain spaces allow spending 3 items in any combination to gain 1 coin, but this is limited to "only once per space."
• Page 6 states that a "2-for-1 resource exchange can be used at any time," but it does not clarify whether this applies to abilities or how multiple exchanges might be handled.
• Page 7 explains dragon abilities, including "if activated" abilities, but does not specify whether multiple benefits can be gained from a single activation.

What is Missing:

• The rulebook does not define whether abilities that allow exchanges can be used repeatedly during a single activation.
• It does not provide a clear resolution process for handling multiple exchanges within one ability.

To answer this question definitively, the rulebook would need to include:

• A clarification on whether abilities can be activated multiple times in one instance.
• Specific rules for resolving multiple exchanges within a single ability.

Source: Wyrmspan Rulebook (pp. 10, 2, 5, 6, 7)